Teresa's TRU Story: Advanced Non–Small Cell Lung Cancer
Advanced non–small cell lung cancer​

TERESA'S TRU STORY

Teresa is a real patient. KEYTRUDA may not work for everyone, but this is her TRU STORY.

See how Teresa remains positive and determined with the support of the people who love her

Teresa's Non–Small Cell Lung Cancer Patient Journey

Teresa's journey

Teresa's Non–Small Cell Lung Cancer Patient Journey: When Teresa Received a Diagnosis of Advanced Lung Cancer, She Wasn't Going to Face It Alone

Family comes first

If you ask Teresa’s family about her, you’ll learn she’s the person they all gather around. Teresa and her older sister Joyce have always known they can rely on each other. Robert, Teresa’s husband, has only grown closer to her during their 44 years of marriage. And her granddaughters Donisha and Armani know Teresa is “the rock of the family...who holds everything together.”

All that love and respect are reflections of Teresa’s own attitude. “I have 4 children, 10 grandkids, and 10 great-grandkids…I just love being there for them, for whatever they need,” she says. Clearly, a big family just means there’s more to cherish.

When Teresa received a diagnosis of advanced lung cancer, she wasn’t going to face it alone.

Finding a path forward

Teresa’s core support team is made up of Joyce and Robert. As Robert puts it, “Joyce has been there like I’ve been there. Teresa needs us more than anything now.”

Teresa knows a combined effort can make a big difference. It’s something she learned during her own past work caring for cancer patients in the hospital. “I ran into people who were alone, with no family, or they had family who just didn’t care. And I tried to be there for them,” she said.

After discussing options with Teresa’s doctor, they agreed KEYTRUDA + chemotherapy was the right treatment for her.

After Discussing Options With Teresa's Doctor, They Agreed KEYTRUDA® (pembrolizumab) With Chemotherapy Was the Right Treatment for Her

Walking the path together

When Teresa started on KEYTRUDA + chemotherapy, Joyce was there with her. “It really helped having her there right beside me,” Teresa says. Even if Joyce can’t make an appointment, Teresa calls her on the phone to talk during her treatment.

They also received the results of Teresa’s first scans together. According to Joyce, it was a day worth remembering. “I was sitting right there,” she recalls.“We cried just a little bit, but it was tears of joy...that was some great news.”

While on treatment, Teresa did experience some fatigue. But like everything else she’s been through, her loved ones were there to help. “It isn’t just her battle. It’s our battle,” says Robert. With that kind of support, Teresa has been able to stay focused on her treatment journey and wants to inspire others to do the same.

Learn About Clinical Trial Data With KEYTRUDA® (pembrolizumab) With Chemotherapy
Stay strong and stay positive, don't give up.
- Teresa

Experiences with KEYTRUDA differ among individuals. KEYTRUDA will not work for everyone, and it’s important to be informed about possible side effects. Always talk to your doctor or health care team if you have questions about your treatment.

FDA-Approved Indications

KEYTRUDA is a prescription medicine used to treat a kind of lung cancer called non–small cell lung cancer (NSCLC).

KEYTRUDA may be used with the chemotherapy medicines pemetrexed and a platinum as your first treatment when your lung cancer has spread (advanced NSCLC) and is a type called "nonsquamous" and your tumor does not have an abnormal "EGFR" or "ALK" gene.

KEYTRUDA may be used with the chemotherapy medicines carboplatin and either paclitaxel or paclitaxel protein-bound as your first treatment when your lung cancer has spread (advanced NSCLC), and is a type called "squamous."

KEYTRUDA may be used alone as your first treatment when your lung cancer has not spread outside your chest (stage III) and you cannot have surgery or chemotherapy with radiation, or your NSCLC has spread to other areas of your body (advanced NSCLC), and your tumor tests positive for "PD-L1and does not have an abnormal "EGFR" or "ALK" gene.

KEYTRUDA may also be used alone for advanced NSCLC if you have tried chemotherapy that contains platinum and it did not work or is no longer working and, your tumor tests positive for "PD-L1and if your tumor has an abnormal "EGFR" or "ALK" gene, you have also received an "EGFR" or "ALK" inhibitor medicine that did not work or is no longer working.

PD-L1 = programmed death ligand 1; EGFR = epidermal growth factor receptor; ALK = anaplastic lymphoma kinase.

Important Safety Information

KEYTRUDA is a medicine that may treat certain cancers by working with your immune system. KEYTRUDA can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen any time during treatment or even after your treatment has ended.

Call or see your health care provider right away if you develop any signs or symptoms of the following problems or if they get worse. These are not all of the signs and symptoms of immune system problems that can happen with KEYTRUDA:

Lung problems: cough, shortness of breath, or chest pain.

Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; or severe stomach-area (abdomen) pain or tenderness.

Liver problems: yellowing of your skin or the whites of your eyes; severe nausea or vomiting; pain on the right side of your stomach area (abdomen); dark urine (tea colored); or bleeding or bruising more easily than normal.

Hormone gland problems: headaches that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increased sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness.

Kidney problems: decrease in the amount of your urine; blood in your urine; swelling of your ankles; loss of appetite.

Skin problems: rash; itching; skin blistering or peeling; painful sores or ulcers in your mouth or in your nose, throat, or genital area; fever or flu-like symptoms; swollen lymph nodes.

Problems can also happen in other organs and tissues. Signs and symptoms of these problems may include: chest pain; irregular heartbeat; shortness of breath; swelling of ankles; confusion; sleepiness; memory problems; changes in mood or behavior; stiff neck; balance problems; tingling or numbness of the arms or legs; double vision; blurry vision; sensitivity to light; eye pain; changes in eyesight; persistent or severe muscle pain or weakness; muscle cramps; low red blood cells; bruising.

Infusion reactions that can sometimes be severe or life-threatening. Signs and symptoms of infusion reactions may include chills or shaking, itching or rash, flushing, shortness of breath or wheezing, dizziness, feeling like passing out, fever, and back pain.

Rejection of a transplanted organ. Your health care provider should tell you what signs and symptoms you should report and they will monitor you, depending on the type of organ transplant that you have had.

Complications, including graft-versus-host disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with KEYTRUDA. Your health care provider will monitor you for these complications.

Getting medical treatment right away may help keep these problems from becoming more serious. Your health care provider will check you for these problems during treatment with KEYTRUDA. They may treat you with corticosteroid or hormone replacement medicines. They may also need to delay or completely stop treatment with KEYTRUDA if you have severe side effects.

Before you receive KEYTRUDA, tell your health care provider if you have immune system problems such as Crohn’s disease, ulcerative colitis, or lupus; have had an organ transplant or have had or plan to have a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic); have had radiation treatment in your chest area; have a condition that affects your nervous system, such as myasthenia gravis or Guillain-Barré syndrome.

If you are pregnant or plan to become pregnant, tell your health care provider. KEYTRUDA can harm your unborn baby. If you are able to become pregnant, you will be given a pregnancy test before you start treatment. Use effective birth control during treatment and for at least 4 months after your final dose of KEYTRUDA. Tell them right away if you think you may be pregnant or you become pregnant during treatment with KEYTRUDA.

Tell your health care provider if you are breastfeeding or plan to breastfeed. It is not known if KEYTRUDA passes into your breast milk. Do not breastfeed during treatment with KEYTRUDA and for 4 months after your final dose of KEYTRUDA.

Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Common side effects of KEYTRUDA when used alone include feeling tired; pain, including pain in muscles, bones or joints, and stomach-area (abdominal) pain; decreased appetite; itching; diarrhea; nausea; rash; fever; cough; shortness of breath; and constipation.

In children, when KEYTRUDA is used alone, fever, vomiting, upper respiratory tract infection, headache, and low levels of white blood cells and red blood cells (anemia) are more common than in adults.

Common side effects of KEYTRUDA when given with certain chemotherapy medicines include feeling tired or weak; nausea; constipation; diarrhea; decreased appetite; rash; vomiting; cough; trouble breathing; fever; hair loss; inflammation of the nerves that may cause pain, weakness, and paralysis in the arms and legs; swelling of the lining of the mouth, nose, eyes, throat, intestines, or vagina; mouth sores; headache; weight loss; stomach-area (abdominal) pain; joint and muscle pain; and trouble sleeping.

Common side effects of KEYTRUDA when given with axitinib include diarrhea; feeling tired or weak; high blood pressure; liver problems; low levels of thyroid hormone; decreased appetite; blisters or rash on the palms of your hands and soles of your feet; nausea; mouth sores or swelling of the lining of the mouth, nose, eyes, throat, intestines, or vagina; hoarseness; rash; cough; and constipation.

These are not all the possible side effects of KEYTRUDA. Talk to your health care provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the accompanying Medication Guide for KEYTRUDA and discuss it with your doctor. The physician Prescribing Information also is available.